JET sort of Retirement Party

Dear Family and Friends,

As you should well have guessed, Rachel's organization of the Retirement party for me was a complete surprise. I had no clue even when we bumped into Bob and Marsha walking in; Rachel told me that she somehow managed to indicate to them that I wasn't aware, which certainly was the case. I can't express my appreciation enough for this and the well wishes I received from others. My birthday was Oct. 3 and since her husband's, Bryan, was Oct. 5, we were just going out to eat dinner together. I assumed her dress was for the party she and Bryan were going to afterwards.

I held off writing this, hoping that Rachel could find the tapes of that night, which unfortunately seem to be carefully stored somewhere. I wanted them for this since my verbal memory always was poor. The fact that the tapes existed is shown in the first image of Conway using the tape recorder. Since I can't quote from them, I am including a few of your gracious comments. I need to put together a name list for those not familiar with some of the others; it will be done sometime, but not too soon.

I want to express our sincere thanks to Joost Businger, without whose invitation to UW we would never had this great opportunity and to Conway Leovy, who is a responsible co-conspirator in many of my Viking Mars Activities. My appreciation goes out to Risto Pellinen and Ari-Matti Harri of the Finnish Meteorology Institute for their fabulous interactions in Mars missions, culminating in our Mars "Climate Lander", MetNet, program now being implemented. I have thoroughly enjoyed working with Fred Weller, Neal Johnson, David Warren, Harry Edmon, and Kristina Katsaros to mention a few who have helped me explore boundary layers on a couple of planets. Thanks to my Mother who told me to go to the top when presented with a problem; its HER FAULT when I go astray and credit when I succeed. Finally, with such great family, friends and colleagues, a few positive results are inevitable.

Although I took a few photos, these were taken by Jim who earns his living as a photographer. He most often shoots catalog for REI, Bon, etc. but is also known as the person to contact in Seattle for difficult problems. Recently someone reccommended him for a World Affairs Council presentation by Condoleezza Rice, where he took 87 Portraits along with other shots.

THANKS

Jim

The photos and web site can be found at, http://www.atmos.washington.edu/~mars/Retirement/

Photo gallery
All Photos courtesy of James G. Tillman
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? Where are the missing MarsGate tapes ?
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Joost Businger

Marsha Baker and Page 2

Kristina Katsaros

Conway Leovy and Page 2

Mike Wallace

More of your good wishes will be scanned.



Why Charlie is important to UW

Ingo's Pond

CASP4 Fourth Community Wide Experiment on the Critical Assessment of Techniques for Protein Structure Prediction (CASP4)



 
One of the most important unsolved problems in Molecular Biology is the protein folding problem, which can be stated simply as: given the sequence of amino acids of a protein, what is its three dimensional structure? What makes this problem so important is the fact that the structure of the protein determines its function. However, the gap between the number of known amino acid sequences and the number of known three dimensional structures grows rapidly.  ... Therefore a computational solution of this problem is more than desirable. ... One of the key ingredients of ROSETTA is a scoring function that assigns a score to three-dimensional structures and guides the search from the extended chain to a protein-like fold. We (the Baker lab) used our folding routine in this year's structure prediction competition (CASP4), and it was quite successful. 
 
To compare the quality of the predictions of the various groups, the submissions for CASP4 were scored by the organizers (2 points for a largely correct prediction, 1 point for a somewhat correct prediction, 0 points otherwise).

The histogram in the left panel below shows the total scores for all groups that submitted predictions for ab initio targets. Since predicting three-dimensional protein structures takes many recources (computer and people time), not all labs were able to submit as many targets as we did, and one could argue that displaying the results as cumulative scores, the way it was done in the histogram on the left, was not completely fair to smaller labs. To account for that, we also show the average score per target submitted (for labs that submitted predictions for more than 5 targets). These data, as a measure of reliability, are shown in the right panel below.  

The UW Baker Lab might not have produced such stunning results if I hadn't hired Charlie Strauss, responsible for this breakthrough, to work on Viking Meteorology data while in high school, thereby helping launch his research career. This dramatically demonstrates the impossibility of predicting the most important benefits of early "venture education" investments in our youth. Jim Tillman, Oct. 2001

For a fair comparison of existing protein structure prediction methods developed in various labs around the world, a semi-annual community wide blind test was implemented. For the Community Wide Experiment on the Critical Assessment of Techniques for Protein Structure Prediction (CASP), some newly solved three-dimensional structures of proteins are withheld, and only their sequences are made public. The structure of those proteins will not be published until a given deadline, which gives CASP participants the chance to submit their predictions for the proteins.


Retirement Activities

My recent, present and future programs consist of a suite of interrelated educational components Live From Earth and Mars -- Science, Technology, Education Partnerships, LFEM -- STEP , a PowerPoint presentation.

These programs have two atmospheric sciences components that are an intergral part of our third component, the Mars MetNet "Climate Lander" program.